Fractional Flow Reserve Assessment of a Significant Coronary Stenosis Masked by a Downstream Serial Lesion
نویسندگان
چکیده
Fractional flow reserve (FFR) has been recognized as an effective tool to determine functional significance in intermediate coronary lesions and FFR-guided percutaneous coronary intervention (PCI) improves clinical outcomes. However, hemodynamic interaction between serial stenoses within one coronary artery complicates the assessment of functional severity of each individual lesion. We present a case in which FFR measurement by intracoronary bolus injection of adenosine helps to make appropriate revascularization decision in serial stenoses when the procedures are performed systemically and properly.
منابع مشابه
True Fractional Flow Reserve of Left Main Coronary Artery Stenosis in the Presence of Downstream Coronary Stenoses.
With great interest I read the recent paper by Fearon et al. (1) in which they assessed the impact of downstream left anterior descending (LAD) or left circumflex (LCX) coronary stenosis on the assessment of fractional flow reserve (FFR) of an left main coronary artery (LMCA) stenosis. They concluded that if the apparent FFR of the LMCA (FFRapp) is >0.85, the true FFR of the LMCA (FFRtrue) is a...
متن کاملLetter by Karabay et al regarding article, "fractional flow reserve assessment of left main stenosis in the presence of downstream coronary stenoses".
BACKGROUND Several studies have shown that fractional flow reserve (FFR) measurement can aid in the assessment of left main coronary stenosis. However, the impact of downstream epicardial stenosis on left main FFR assessment with the pressure wire in the nonstenosed downstream vessel remains unknown. METHODS AND RESULTS Variable stenoses were created in the left main coronary arteries and dow...
متن کاملLetter by Layland et al regarding article, "Validation of intravascular ultrasound-derived parameters with fractional flow reserve for assessment of coronary stenosis severity".
To the Editor: We read with great interest the study by Kang et al 1 that explored the relationship between intravascular ultrasound parameters and fractional flow reserve (FFR) in the assessment of intermediate coronary stenoses. 1 We congratulate the authors, who concluded that lesions with a mean luminal area of Ͻ2.4 mm 2 had a high sensitivity and negative predictive value to predict FFR Ͻ0...
متن کاملSignificance of Microvascular Function in Visual—Functional Mismatch Between Invasive Coronary Angiography and Fractional Flow Reserve
BACKGROUND Despite a moderate correlation between angiographical stenosis and physiological significance, the mechanism of discordance has not been fully elucidated, particularly regarding the significance of microvascular function. This study sought to clarify whether microvascular function affects visual-functional mismatch between quantitative coronary angiography (QCA) and fractional flow r...
متن کاملMisinterpretation of Stenosis Severity in the Presence of Serial Coronary Stenoses
Diagnosis of the functional severity of an epicardial coronary stenosis using parameters like Fractional Flow Reserve, FFR (ratio of distal to proximal pressure of a stenotic region), might be affected in the presence of an additional downstream stenosis. In order to assess this effect, we have performed an in-vitro experiment which is used to validate a computational study. Three combinations ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016